Cough Drops
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A throat lozenge (also known as a cough drop, sore throat sweet, troche, cachou, pastille or cough sweet) is a small, typically medicated tablet intended to be dissolved slowly in the mouth to temporarily stop coughs, lubricate, and soothe irritated tissues of the
throat In vertebrate anatomy, the throat is the front part of the neck, internally positioned in front of the vertebrae. It contains the pharynx and larynx. An important section of it is the epiglottis, separating the esophagus from the trachea (windpipe ...
(usually due to a
sore throat Sore throat, also known as throat pain, is pain or irritation of the throat. Usually, causes of sore throat include * viral infections * group A streptococcal infection (GAS) bacterial infection * pharyngitis (inflammation of the throat) * tonsi ...
or
strep throat Streptococcal pharyngitis, also known as streptococcal sore throat (strep throat), is pharyngitis (an infection of the pharynx, the back of the throat) caused by ''Streptococcus pyogenes'' a gram-positive, group A streptococcus. Common symptom ...
), possibly from the
common cold The common cold or the cold is a viral infectious disease of the upper respiratory tract that primarily affects the respiratory mucosa of the nose, throat, sinuses, and larynx. Signs and symptoms may appear fewer than two days after exposu ...
or
influenza Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms ...
. Cough tablets have taken the name lozenge, based on their original shape, a diamond.


Ingredients

Lozenges may contain
benzocaine Benzocaine, sold under the brand name Orajel amongst others, is an ester local anesthetic commonly used as a topical pain reliever or in cough drops. It is the active ingredient in many over-the-counter anesthetic ointments such as products f ...
, an
anaesthetic An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia ⁠— ⁠in other words, to result in a temporary loss of sensation or awareness. They may be divided into two ...
, or
eucalyptus oil Eucalyptus oil is the generic name for distilled oil from the leaf of ''Eucalyptus'', a genus of the plant family Myrtaceae native to Australia and cultivated worldwide. Eucalyptus oil has a history of wide application, as a pharmaceutical, ant ...
. Non-menthol throat lozenges generally use either
zinc gluconate glycine Zinc gluconate is the zinc salt of gluconic acid. It is an ionic compound consisting of two anions of gluconate for each zinc(II) cation. Zinc gluconate is a popular form for the delivery of zinc as a dietary supplement providing 14.35% elemen ...
or
pectin Pectin ( grc, πηκτικός ': "congealed" and "curdled") is a heteropolysaccharide, a structural acid contained in the primary lamella, in the middle lamella, and in the cell walls of terrestrial plants. The principal, chemical component of ...
as an oral demulcent. Several brands of throat lozenges contain
dextromethorphan Dextromethorphan (DXM) is a medication most often used as a cough suppressant in over-the-counter cold and cough medicines. It is sold in syrup, tablet, spray, and lozenge forms. In 2022, the FDA approved a formulation of it combined with bu ...
. Other varieties such as Halls contain
menthol Menthol is an organic compound, more specifically a monoterpenoid, made synthetically or obtained from the oils of corn mint, peppermint, or other mints. It is a waxy, clear or white crystalline substance, which is solid at room temperature and ...
,
peppermint oil Peppermint extract is an herbal extract of peppermint (''Mentha × piperita'') made from the essential oils of peppermint leaves. Peppermint is a hybrid of water mint and spearmint and was indigenous to Europe and the Middle East before it became c ...
and/or
spearmint Spearmint, also known as garden mint, common mint, lamb mint and mackerel mint, is a species of mint, ''Mentha spicata'' (, native to Europe and southern temperate Asia, extending from Ireland in the west to southern China in the east. It is nat ...
as their
active ingredient An active ingredient is any ingredient that provides biologically active or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the body of humans or animals. T ...
(s).
Honey Honey is a sweet and viscous substance made by several bees, the best-known of which are honey bees. Honey is made and stored to nourish bee colonies. Bees produce honey by gathering and then refining the sugary secretions of plants (primar ...
lozenges are also available. The purpose of the throat lozenge is to calm the irritation that may be felt in the throat while swallowing, breathing, or even drinking certain fluids. However, one study found that excessive use of menthol cough drops can prolong coughs rather than relieve them.


History

Candies to soothe the throat date back to 1000 BC in
Egypt Egypt ( ar, مصر , ), officially the Arab Republic of Egypt, is a transcontinental country spanning the northeast corner of Africa and southwest corner of Asia via a land bridge formed by the Sinai Peninsula. It is bordered by the Mediter ...
's
Twentieth Dynasty The Twentieth Dynasty of Egypt (notated Dynasty XX, alternatively 20th Dynasty or Dynasty 20) is the third and last dynasty of the Ancient Egyptian New Kingdom period, lasting from 1189 BC to 1077 BC. The 19th and 20th Dynasties furthermore togeth ...
, when they were made from honey flavored with
citrus ''Citrus'' is a genus of flowering plant, flowering trees and shrubs in the rue family, Rutaceae. Plants in the genus produce citrus fruits, including important crops such as Orange (fruit), oranges, Lemon, lemons, grapefruits, pomelos, and lim ...
, herbs, and spices. In the 19th century, physicians discovered
morphine Morphine is a strong opiate that is found naturally in opium, a dark brown resin in poppies (''Papaver somniferum''). It is mainly used as a analgesic, pain medication, and is also commonly used recreational drug, recreationally, or to make ...
and
heroin Heroin, also known as diacetylmorphine and diamorphine among other names, is a potent opioid mainly used as a recreational drug for its euphoric effects. Medical grade diamorphine is used as a pure hydrochloride salt. Various white and brow ...
, which suppress coughing at its source—the brain. Popular formulations of that era included
Smith Brothers The Smith Brothers were makers of the first cough drops produced and advertised in the United States, becoming one of the most famous brands in the country in its day. History William Wallace Smith I (1830–1913) and Andrew Smith (1836–1895 ...
Cough Drops, first advertised in 1852, and
Luden's Luden's is an American brand of cough drop that is currently manufactured and sold in the US by Prestige Consumer Healthcare. Company headquarters are in Tarrytown, New York. Luden's products include Blue Raspberry, Honey Lemon, Honey Licorice, Ki ...
, created in 1879. Concern over the risk of
opioid dependence Opioid use disorder (OUD) is a substance use disorder characterized by cravings for opioids, continued use despite physical and/or psychological deterioration, increased tolerance with use, and withdrawal symptoms after discontinuing opioids. Op ...
led to the development of alternative medications.


Brands

*
Cēpacol Cepacol ( styled Cēpacol) is an American brand of personal hygiene products, as well as for relief of sore throat. It is distributed in the US by Reckitt. The brand was originally owned by J.B. Williams. Following acquisition by Combe Incorp ...
* Chloraseptic *
Fisherman's Friend Fisherman's Friend is a brand of strong menthol lozenges manufactured by the Lofthouse company in Fleetwood, Lancashire, England. History Fisherman's Friend was originally developed by pharmacist James Lofthouse in 1865 to relieve various ...
* Halls *
Läkerol Läkerol is a Swedish brand of candies. The candies are sugar-free pastilles with the major ingredient being gum arabic. The candies are produced in a variety of flavors. The candy is produced by the Swedish confectionery company, Cloetta. L ...
*
Lockets Lockets are a confectionery produced by the Wrigley Company in the United Kingdom, UK and Czech Republic. They are sold as medicated supplement to help nasal congestion and sore throats. Flavours They are available in multiple flavours including ...
*
Luden's Luden's is an American brand of cough drop that is currently manufactured and sold in the US by Prestige Consumer Healthcare. Company headquarters are in Tarrytown, New York. Luden's products include Blue Raspberry, Honey Lemon, Honey Licorice, Ki ...
*
Pine Bros. Pine Bros. is a US manufacturer of throat drops. John Herman Pine and George William Pine were Philadelphia confectioner brothers. They emigrated from Germany in the 1860s with their parents, Frederick Pine and Margaretta Knopple Pine. In 1870 th ...
*
Ricola Ricola Ltd./Ricola AG is a Swiss manufacturer of cough drops and breath mints. The head office of Ricola is located in Laufen, Basel-Country. Business Ricola listed sales of 307.2 million Swiss francs in 2016 and employs 400 workers. Around ...
*
Robitussin Cold medicines are a group of medications taken individually or in combination as a treatment for the symptoms of the common cold and similar conditions of the upper respiratory tract. The term encompasses a broad array of drugs, including a ...
*
Smith Brothers The Smith Brothers were makers of the first cough drops produced and advertised in the United States, becoming one of the most famous brands in the country in its day. History William Wallace Smith I (1830–1913) and Andrew Smith (1836–1895 ...
*
Strepsils Strepsils is a brand of throat lozenges manufactured by Reckitt. Strepsils throat lozenges are used to relieve discomfort caused by mouth and throat infections. Ingredients The primary active ingredients are dichlorobenzyl alcohol and amylmet ...
*
Sucrets Dyclonine (Dyclocaine) is an oral anaesthetic that is the active ingredient of Sucrets, an over-the-counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydr ...
*
Ülker Ülker is a Turkish multinational food and beverage manufacturer based in Istanbul, Turkey. Its products are exported internationally, to 110 countries. Ülker's core products are biscuits, cookies, crackers, and chocolates, although it has ex ...
* Troketts * Tunes *Tyrozets (now discontinued) *
Vicks Vicks is an American brand of over-the-counter medications owned by the American companies Procter & Gamble and Helen of Troy Limited. Vicks manufactures NyQuil and its sister medication, DayQuil as well as other medications in the “Quil” lin ...
* Strep-Drops *
Victory V Victory V is a British brand of liquorice-flavoured cough medicine, lozenges. Originally manufactured in Nelson, Lancashire, Nelson, Lancashire, they were devised by Thomas Fryer and Edward Smith MD in 1864 and were initially made by hand to en ...
*
Vigroids Vigroids (formerly Nigroids) was the brand name of a liquorice sweet. The small black pellets were particularly marketed as an expectorant lozenge for singers, using the slogan "for clarity of voice". The product was manufactured by Ernest Jacks ...
* Zubes (now discontinued)


See also

*
Pastille A pastille is a type of sweet or medicinal pill made of a thick liquid that has been solidified and is meant to be consumed by light chewing and allowing it to dissolve in the mouth. The term is also used to describe certain forms of incense. ...
*
Mint (candy) A mint or breath mint is a food item often consumed as an after-meal refreshment or before business and social engagements to improve breath odor. Mints are commonly believed to soothe the stomach given their association with natural byproducts ...


References


External links


Ingredients of a throat lozenge
Health Canada {{DEFAULTSORT:Throat Lozenge Drug delivery devices Dosage forms